Presentation:
Conformational Dynamics of the Mre11-Rad50-Nbs1 complex in DNA double-strand break repair

Bio

Karl-Peter Hopfner studied biology and biophysics at the Universities of Regensburg (Germany) and Washington University Medical School in St. Louis (USA). In 1994, he joined the department of structure research (Prof. Robert Huber) at the Max-Planck-Institute for Biochemistry to work on his PhD thesis on the structure and function of blood coagulation factors. After obtaining his PhD in 1997 he went to the Scripps Research Institute (La Jolla, USA) to study the structural mechanism of DNA double-strand break repair in the research group of John Tainer. He continued working on DNA repair and chromatin associated proteins after he became tenure track assistant professor at the Gene Center of the Ludwig-Maximilians-University of Munich (2001). Karl-Peter Hopfner is now full professor of biochemistry at the Gene Center and his group studies the molecular mechanisms of sensing and signaling of DNA damage and pathogenic nucleic acids.

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