Presentation:
The role of the RSC chromatin remodelling complex in DNA damage responses

Bio

Jessica Downs began studying DNA damage responses during her PhD at Cambridge University. As a post-doc in Professor Steve Jackson’s lab, she developed her interest in understanding the impact of chromatin structure on DNA repair and genome stability. She was awarded the Jenner Fellowship from the Lister Institute of Preventive Medicine and started her own laboratory in the Department of Biochemistry at Cambridge University in 2002. She moved her lab to the MRC Genome Damage and Stability Centre at the University of Sussex in 2007. A major focus of the current research in her lab is on the molecular mechanisms by which large, multi-subunit chromatin remodeling complexes contribute to the maintenance of genome stability.

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